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Bulletin de la Société de Pathologie Exotique

0037-9085
 

 ARTICLE VOL 111/4 - 2018  - pp.197-198  - doi:10.3166/bspe-2018-0046
TITLE
EDITORIAL. Threats to the Effectiveness of Malaria Treatment

ABSTRACT

In reaction to the speed and ease with which a high level of resistance against P. falciparum was induced in vivo in a mouse NOD/SCID IL-Ry-/- model by sub-therapeutic doses of artesunate [2], this text begins a plea for concrete measures to limit the risk of eventually appearing the same phenomenon in the field, including a strengthening of the fight against the use of artesunate oral monotherapy, tablet often under-dosed or artemisinin herbal tea and the adoption of more reliable and more efficient means than those currently used to detect the emergence of resistance earlier and a relaunch of the search for new antimalarials.



AUTEUR(S)
Jean-François PAYS

KEYWORDS
malaria, artesunate, atemisinin, quinine, resistance, antimalarials, NOD/SCID IL-Ry-/- mice, public health

LANGUE DE L'ARTICLE
Anglais

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